Grand Avenue, South San Francisco, California 94080
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$1,248,000 USD

Single Family Home for Sale, Grand Avenue, South San Francisco, California 94080

  • MLS#550441684
  • 3
  • 4
  • 151 m² (1,630 ft²)

Listed By Christie's International Real Estate Sereno

The Single Family Home for Sale located at Grand Avenue, South San Francisco, California 94080 is currently for sale. Grand Avenue, South San Francisco, California 94080 is listed for $1,248,000. This property has 3 bedrooms, 4 bathrooms.

Date Updated : Sep 1, 2026
Christie's International Real Estate Sereno

Property features

Property

  • Property size: 151 m² (1,630 ft²)

Lot/Land

  • Land/Lot size: 325 m² (3,500 ft²)

Construction

  • Year built: 1895
  • Roofing: Shingle
  • Construction: No Common Walls

Bedrooms

  • Bedrooms: 3

Bathrooms

  • Total bathrooms: 4
  • Full bathrooms: 4

Interior Features

  • Windows: Skylights

Heating and Cooling

  • Heating System: Central

Description

Ideally located near Downtown South San Francisco and the cities thriving biotech and life-sciences corridor, 643 Grand Avenue where space, comfort, and a remarkable garden setting come together in the heart of South San Francisco. 643 Grand Avenue offers a spacious and versatile layout with excellent access to major transportation and employment centers. The home features 3 bedrooms and 4 bathrooms, with a private full bathroom for each bedroom. Additional highlights include high ceilings, abundant natural light, hardwood floors, a full basement with ample storage, and a detached 2-car garage equipped with a 220-volt outlet for EV charging. The home also features a water purification system, tankless water heater, and water softener. The quaint lot includes a freshly manicured organic vegetable garden with sunflowers and offers potential for an ADU. Conveniently located near Downtown South San Francisco, Genentech, Caltrain, US-101, and I-280.

Location

Grand Avenue, South San Francisco, California 94080

Grand Avenue, South San Francisco, California 94080